Tumor Immunology
Tumor Immunology is determining the function and behaviors of innate and adaptive immune cells in health and disease, including the interactions with their microenvironment. Understanding the essential principles underlying immune cell development, activation, regulation, differentiation and death also because the molecular mechanisms underlying diversity and plasticity of the system may be a prerequisite for the planning of targeted manipulation strategies to guard from cancer, autoimmunity and infection and to foster and devise the event of novel therapeutic approaches. To address their research questions the individual groups, develop and use sophisticated experimental model systems and technologies like structural biology, genetic barcoding and high-throughput single cell analysis platforms.
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